Endogenous laminin is required for human airway smooth muscle cell maturation

<p>Abstract</p> <p>Background</p> <p>Airway smooth muscle (ASM) contraction underlies acute bronchospasm in asthma. ASM cells can switch between a synthetic-proliferative phenotype and a contractile phenotype. While the effects of extracellular matrix (ECM) components o...

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Bibliographic Details
Main Authors: Tran Thai, McNeill Karol D, Gerthoffer William T, Unruh Helmut, Halayko Andrew J
Format: Article
Language:English
Published: BMC 2006-09-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/117