Optimization of Field Design in the Treatment of Rectal Cancer with Intensity Modulated Proton Beam Radiation Therapy: How Many Fields Are Needed to Account for Rectal Distension Uncertainty?

Purpose: Preoperative chemoradiation represents the standard of care in patients with locally advanced rectal cancer. Robustness is often compromised in the setting of proton beam therapy owing to the sensitivity of proton particles to tissue heterogeneity, such as with intestinal gas. The ideal bea...

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Bibliographic Details
Main Authors: Jacob S. Parzen, MD, Weili Zheng, PhD, Xiaoqiang Li, PhD, Xuanfeng Ding, PhD, Peyman Kabolizadeh, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S245210942100107X