Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery.

Targeted sequencing is a cost-efficient way to obtain answers to biological questions in many projects, but the choice of the enrichment method to use can be difficult. In this study we compared two hybridization methods for target enrichment for massively parallel sequencing and single nucleotide p...

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Bibliographic Details
Main Authors: Anna Kiialainen, Olof Karlberg, Annika Ahlford, Snaevar Sigurdsson, Kerstin Lindblad-Toh, Ann-Christine Syvänen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3036585?pdf=render