Insights Into Unveiling a Potential Role of Tertiary Lymphoid Structures in Metastasis

Insights Into Unveiling a Potential Role of Tertiary Lymphoid Structures in Metastasis

Tertiary lymphoid structures (TLSs) develop in non-lymphatic tissue in chronic inflammation and cancer. TLS can mature to lymph node (LN) like structures with germinal centers and associated vasculature. TLS neogenesis in cancer is highly varied and tissue dependent. The role of TLS in adaptive anti...

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Bibliographic Details
Main Authors: Rami Mustapha, Kenrick Ng, James Monypenny, Tony Ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
TLS
metastasis
premetastatic niche
high endothelial venule (HEV)
lymphangiogeneis
tissue stress
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.661516/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.661516/full

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