PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes

PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes

Background/Aims: Myocardial ischemia/reperfusion (I/R) or hypoxia/reoxygenation (H/R) injury is always characterized by Ca2+ overload, energy metabolism disorder and necrocytosis of cardiomyocytes. We showed previously that chronic intermittent hypobaric hypoxia (CIHH) improves cardiac function duri...

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Bibliographic Details
Main Authors: Shuo Gu, Hong Hua, Xinqi Guo, Zhanfeng Jia, Yi Zhang, Leonid N. Maslov, Xiangjian Zhang, Huijie  Ma
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Chronic intermittent hypobaric hypoxia
Cardiomyocytes
Calcium overload
PGC-1α
Energy metabolism
Hypoxia/reoxygenation
Online Access:https://www.karger.com/Article/FullText/494869

Internet

https://www.karger.com/Article/FullText/494869

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