High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

Abstract Background Humanity has become largely dependent on artemisinin derivatives for both the treatment and control of malaria, with few alternatives available. A Plasmodium falciparum phenotype with delayed parasite clearance during artemisinin-based combination therapy has established in South...

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Bibliographic Details
Main Authors: Rajeev K. Tyagi, Patrick J. Gleeson, Ludovic Arnold, Rachida Tahar, Eric Prieur, Laurent Decosterd, Jean-Louis Pérignon, Piero Olliaro, Pierre Druilhe
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Medicine
Subjects:
Malaria
P. falciparum
Artemisinin
Resistance
Artesunate
Quinine
Online Access:http://link.springer.com/article/10.1186/s12916-018-1156-x

Internet

http://link.springer.com/article/10.1186/s12916-018-1156-x

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