Modeling the Mycobacterium tuberculosis granuloma – The critical battlefield in host immunity and disease

Granulomas are the hallmark of Mycobacterium tuberculosis (M.tb) infection and thus sit at the center of tuberculosis (TB) immunopathogenesis. TB can result from either early progression of a primary granuloma during the infection process or reactivation of an established granuloma in a latently inf...

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Bibliographic Details
Main Authors: Evelyn eGuirado, Larry eSchlesinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00098/full