Liver Sinusoidal Endothelial Cells Promote the Expansion of Human Cord Blood Hematopoietic Stem and Progenitor Cells

Liver Sinusoidal Endothelial Cells Promote the Expansion of Human Cord Blood Hematopoietic Stem and Progenitor Cells

Cord blood (CB) is an attractive source of hematopoietic stem cells (HSCs) for hematopoietic cell transplantation. However, its application remains limited due to the low number of HSCs/progenitors in a single CB unit and its notoriously difficulty in expanding ex vivo. Here, we demonstrated that th...

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Bibliographic Details
Main Authors: Huilin Li, Haiyun Pei, Xiaoyan Xie, Sihan Wang, Yali Jia, Bowen Zhang, Zeng Fan, Yiming Liu, Yun Bai, Yi Han, Lijuan He, Xue Nan, Wen Yue, Xuetao Pei
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
liver sinusoidal endothelial cells
hematopoietic stem and progenitor cells
expansion
transplantation
microenvironment
Online Access:https://www.mdpi.com/1422-0067/20/8/1985

Internet

https://www.mdpi.com/1422-0067/20/8/1985

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