The Haematopoietic Stem Cell Niche: New Insights into the Mechanisms Regulating Haematopoietic Stem Cell Behaviour

The concept of the haematopoietic stem cell (HSC) niche was formulated by Schofield in the 1970s, as a region within the bone marrow containing functional cell types that can maintain HSC potency throughout life. Since then, ongoing research has identified numerous cell types and a plethora of signa...

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Bibliographic Details
Main Authors: Andrew J. Lilly, William E. Johnson, Christopher M. Bunce
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.4061/2011/274564