Structural Basis and Evolution of Glycan Receptor Specificities within the Polyomavirus Family

Virus attachment to cell surface receptors is critical for productive infection. In this study, we have used a structure-based approach to investigate the cell surface recognition event for New Jersey polyomavirus (NJPyV) and human polyomavirus 12 (HPyV12). These viruses belong to the polyomavirus f...

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Main Authors: Luisa J. Ströh, Nils H. Rustmeier, Bärbel S. Blaum, Josephine Botsch, Philip Rößler, Florian Wedekink, W. Ian Lipkin, Nischay Mishra, Thilo Stehle
Format: Article
Language:English
Published: American Society for Microbiology 2020-07-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00745-20