Ciprofloxacin Enhances the Chemosensitivity of Cancer Cells to ABCB1 Substrates

ABCB1 is one of the major drug efflux transporters that is known to cause multidrug resistance (MDR) in cancer patients receiving chemotherapy for the treatment of solid tumors and hematological malignancies. Inhibition of ABCB1 efflux function is important for maintaining the intracellular concentr...

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Bibliographic Details
Main Authors: Pranav Gupta, Hai-Ling Gao, Yunali V. Ashar, Nishant M. Karadkhelkar, Sabesan Yoganathan, Zhe-Sheng Chen
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/20/2/268