Plasma gelsolin depletion and circulating actin in sepsis: a pilot study.

Depletion of the circulating actin-binding protein, plasma gelsolin (pGSN) has been described in septic patients and animals. We hypothesized that the extent of pGSN reduction correlates with outcomes of septic patients and that circulating actin is a manifestation of sepsis.We assayed pGSN in plasm...

Full description

Bibliographic Details
Main Authors: Po-Shun Lee, Sanjay R Patel, David C Christiani, Ednan Bajwa, Thomas P Stossel, Aaron B Waxman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2577888?pdf=render