Toxicokinetics of the plasticizer, N-butylbenzenesulfonamide, in plasma and brain following oral exposure in rodents: Route, species, and sex comparison

Toxicokinetics of the plasticizer, N-butylbenzenesulfonamide, in plasma and brain following oral exposure in rodents: Route, species, and sex comparison

N-Butylbenzenesulfonamide (NBBS) is a widely used plasticizer and hence there is potential for human exposure via oral routes. This work investigates the toxicokinetic behavior of NBBS in rodents following a single gavage (20, 60, and 200 mg/kg body weight) or multi-day feed administration (500, 100...

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Bibliographic Details
Main Authors: Suramya Waidyanatha, Seth Gibbs, Natalie South, Jeremy P. Smith, Esra Mutlu, Brian Burback, Yu Cao, Cynthia V. Rider
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
N-butylbenzenesulfonamide
plasticizer
systemic exposure
half-life
clearance
rodents
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750020303309

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http://www.sciencedirect.com/science/article/pii/S2214750020303309

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