Estrogen provides neuroprotection against brain edema and blood brain barrier disruption through both estrogen receptors α and β following traumatic brain injury

Estrogen provides neuroprotection against brain edema and blood brain barrier disruption through both estrogen receptors α and β following traumatic brain injury

Objective(s):Estrogen (E2) has neuroprotective effects on blood-brain-barrier (BBB) after traumatic brain injury (TBI). In order to investigate the roles of estrogen receptors (ERs) in these effects, ER-α antagonist (MPP) and, ER-β antagonist (PHTPP), or non-selective estrogen receptors antagonist (...

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Bibliographic Details
Main Authors: Vida Naderi, Mohammad Khaksari, Reza Abbasi, Fatemeh Maghool
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Blood-brain-barrier Brain edema ERα antagonist ERβ antagonist ICI182780 Traumatic brain injury
Online Access:http://ijbms.mums.ac.ir/pdf_4015_1e43b03e50c1729c61f43c3df20b7507.html

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http://ijbms.mums.ac.ir/pdf_4015_1e43b03e50c1729c61f43c3df20b7507.html

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