Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.

Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.

Gene expression profiling of peripheral blood mononuclear cells (PBMCs) is a powerful tool for the identification of surrogate markers involved in disease processes. The hypothesis tested in this study was that chronic exposure of PBMCs to a hypertensive environment in remodeled pulmonary vessels wo...

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Bibliographic Details
Main Authors: Chris Cheadle, Alan E Berger, Stephen C Mathai, Dmitry N Grigoryev, Tonya N Watkins, Yumiko Sugawara, Sangjucta Barkataki, Jinshui Fan, Meher Boorgula, Laura Hummers, Ari L Zaiman, Reda Girgis, Michael A McDevitt, Roger A Johns, Frederick Wigley, Kathleen C Barnes, Paul M Hassoun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335832?pdf=render

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http://europepmc.org/articles/PMC3335832?pdf=render

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