Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis.

BACKGROUND: Tuberculin-specific T-cell responses have low diagnostic specificity in BCG vaccinated populations. While subunit-antigen (e.g. ESAT-6, CFP-10) based tests are useful for diagnosing latent tuberculosis infection, there is no reliable immunological test for active pulmonary tuberculosis....

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Bibliographic Details
Main Authors: Mathias Streitz, Lydia Tesfa, Vedat Yildirim, Ali Yahyazadeh, Timo Ulrichs, Rodica Lenkei, Ali Quassem, Gerd Liebetrau, Laurel Nomura, Holden Maecker, Hans-Dieter Volk, Florian Kern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1936433?pdf=render