Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

Abstract Background Parkinson’s disease (PD) is a systemic disease clinically defined by the degeneration of dopaminergic neurons in the brain. While alterations in the gut microbiome composition have been reported in PD, their functional consequences remain unclear. Herein, we addressed this questi...

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Bibliographic Details
Main Authors: Federico Baldini, Johannes Hertel, Estelle Sandt, Cyrille C. Thinnes, Lorieza Neuberger-Castillo, Lukas Pavelka, Fay Betsou, Rejko Krüger, Ines Thiele, on behalf of the NCER-PD Consortium
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Biology
Subjects:
Parkinson’s disease
Gut microbiome
Computational modelling
Metabolic modelling
Transsulfuration pathway
Online Access:http://link.springer.com/article/10.1186/s12915-020-00775-7

Internet

http://link.springer.com/article/10.1186/s12915-020-00775-7

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