Epitope analysis and protection by a ROP19 DNA vaccine against Toxoplasma gondii

Epitope analysis and protection by a ROP19 DNA vaccine against Toxoplasma gondii

We used bioinformatics approaches to identify B-cell and T-cell epitopes on the ROP19 protein of Toxoplasma gondii. Then, we constructed plasmids with ROP19 (pEGFP-C1-ROP19) and injected them into BALB/c mice to test the immunoprotection induced by this vaccine candidate. The results showed that imm...

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Bibliographic Details
Main Authors: Zhou Jian, Wang Lin, Lu Gang, Zhou Aihua, Zhu Meiyan, Li Qihang, Wang Zhilin, Arken Miradel, Wang Ao, He Shenyi
Format: Article
Language:English
Published: EDP Sciences 2016-01-01
Series:Parasite
Subjects:
DNA vaccine
Immunity
ROP19
Toxoplasma gondii
BALB/c mice
Online Access:http://dx.doi.org/10.1051/parasite/2016017

Internet

http://dx.doi.org/10.1051/parasite/2016017

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