Molecular evidence for a functional ecdysone signaling system in Brugia malayi.

BACKGROUND:Filarial nematodes, including Brugia malayi, the causative agent of lymphatic filariasis, undergo molting in both arthropod and mammalian hosts to complete their life cycles. An understanding of how these parasites cross developmental checkpoints may reveal potential targets for intervent...

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Bibliographic Details
Main Authors: George Tzertzinis, Ana L Egaña, Subba Reddy Palli, Marc Robinson-Rechavi, Chris R Gissendanner, Canhui Liu, Thomas R Unnasch, Claude V Maina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2834746?pdf=render