The equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila.

The number of synapses is a major determinant of behavior and many neural diseases exhibit deviations in that number. However, how signaling pathways control this number is still poorly understood. Using the Drosophila larval neuromuscular junction, we show here a PI3K-dependent pathway for synaptog...

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Bibliographic Details
Main Authors: Sheila Jordán-Álvarez, Elena Santana, Sergio Casas-Tintó, Ángel Acebes, Alberto Ferrús
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5593197?pdf=render