FGF21-Mediated Improvements in Glucose Clearance Require Uncoupling Protein 1

Fibroblast growth factor 21 (FGF21)-mediated weight loss and improvements in glucose metabolism correlate with increased uncoupling protein 1 (Ucp1) levels in adipose tissues, suggesting that UCP1-dependent thermogenesis may drive FGF21 action. It was reported that FGF21 is equally effective at redu...

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Bibliographic Details
Main Authors: Michelle M. Kwon, Shannon M. O’Dwyer, Robert K. Baker, Scott D. Covey, Timothy J. Kieffer
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715011754