FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation.

FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation.

Successful embryo implantation requires a receptive endometrium. Poor uterine receptivity can account for implantation failure in women who experience recurrent pregnancy loss or multiple rounds of unsuccessful in vitro fertilization cycles. Here, we demonstrate that the transcription factor Forkhea...

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Bibliographic Details
Main Authors: Yasmin M Vasquez, Xiaoqiu Wang, Margeaux Wetendorf, Heather L Franco, Qianxing Mo, Tianyuan Wang, Rainer B Lanz, Steven L Young, Bruce A Lessey, Thomas E Spencer, John P Lydon, Francesco J DeMayo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007787

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https://doi.org/10.1371/journal.pgen.1007787

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