Panobinostat and its combination with 3-deazaneplanocin-A induce apoptosis and inhibit In vitro tumorigenesis and metastasis in GOS-3 glioblastoma cell lines
Aim: Glioblastoma is the most malignant primary brain tumor. The treatment consists of surgery, with or without radiotherapy, and temozolomide, with a life expectancy of 12–15 months after diagnosis. Glioblastoma is resistant to conventional antitumor therapies. In this work, we present a preliminar...
Main Authors: | Javier de la Rosa, Alejandro Urdiciain, Juan Jesús Aznar-Morales, Bárbara Meléndez, Juan A Rey, Miguel A Idoate, Javier S Castresana |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2018-01-01
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Series: | Cancer Translational Medicine |
Subjects: | |
Online Access: | http://www.cancertm.com/article.asp?issn=2395-3977;year=2018;volume=4;issue=2;spage=39;epage=47;aulast=de |
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