Molecular Insights into the Classification of Luminal Breast Cancers: The Genomic Heterogeneity of Progesterone-Negative Tumors

Molecular Insights into the Classification of Luminal Breast Cancers: The Genomic Heterogeneity of Progesterone-Negative Tumors

Estrogen receptor (ER)-positive progesterone receptor (PR)-negative breast cancers are infrequent but clinically challenging. Despite the volume of genomic data available on these tumors, their biology remains poorly understood. Here, we aimed to identify clinically relevant subclasses of ER+/PR&...

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Bibliographic Details
Main Authors: Gianluca Lopez, Jole Costanza, Matteo Colleoni, Laura Fontana, Stefano Ferrero, Monica Miozzo, Nicola Fusco
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
progesterone receptor negative
mutational profiling
PI3K pathway
TP53
Online Access:https://www.mdpi.com/1422-0067/20/3/510

Internet

https://www.mdpi.com/1422-0067/20/3/510

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