Clinical application of whole transcriptome sequencing for the classification of patients with acute lymphoblastic leukemia

Clinical application of whole transcriptome sequencing for the classification of patients with acute lymphoblastic leukemia

Abstract Background Considering the clinical and genetic characteristics, acute lymphoblastic leukemia (ALL) is a rather heterogeneous hematological neoplasm for which current standard diagnostics require various analyses encompassing morphology, immunophenotyping, cytogenetics, and molecular analys...

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Bibliographic Details
Main Authors: Wencke Walter, Rabia Shahswar, Anna Stengel, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Cancer
Subjects:
Patient classification
Whole transcriptome sequencing
Fusion transcript calling
Gene expression profiling
Online Access:https://doi.org/10.1186/s12885-021-08635-5

Internet

https://doi.org/10.1186/s12885-021-08635-5

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