miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through KLF4

miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through KLF4

Abstract Background Aging is one of the key factors that regulate the function of human bone marrow mesenchymal stem cells (hBM-MSCs) and related changes in microRNA (miRNA) expression. However, data reported on aging-related miRNA changes in hBM-MSCs are limited. Methods We demonstrated previously...

Full description

Bibliographic Details
Main Authors: Jun Dong, Zhenhui Zhang, Hongshen Huang, Pei Mo, Chuanfan Cheng, Jianwei Liu, Weizhao Huang, Chaowei Tian, Chongyu Zhang, Jiao Li
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Stem Cell Research & Therapy
Subjects:
Aging
MicroRNA
Rejuvenation
Myocardial infarction
Online Access:http://link.springer.com/article/10.1186/s13287-018-0895-0

Internet

http://link.springer.com/article/10.1186/s13287-018-0895-0

Similar Items