Working memory deficits in schizophrenia are associated with the rs34884856 variant and expression levels of the NR4A2 gene in a sample Mexican population: a case control study

Working memory deficits in schizophrenia are associated with the rs34884856 variant and expression levels of the NR4A2 gene in a sample Mexican population: a case control study

Abstract Background Cognitive functions represent useful endophenotypes to identify the association between genetic variants and schizophrenia. In this sense, the NR4A2 gene has been implicated in schizophrenia and cognition in different animal models and clinical trials. We hypothesized that the NR...

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Bibliographic Details
Main Authors: Elizabeth Ruiz-Sánchez, Janet Jiménez-Genchi, Yessica M. Alcántara-Flores, Carlos J. Castañeda-González, Carlos L. Aviña-Cervantes, Petra Yescas, María del Socorro González-Valadez, Nancy Martínez-Rodríguez, Antonio Ríos-Ortiz, Martha González-González, María E. López-Navarro, Patricia Rojas
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Psychiatry
Subjects:
Schizophrenia
NR4A2 genetic variants
NR4A2 mRNA levels
Cognition
Endophenotype
Working memory
Online Access:https://doi.org/10.1186/s12888-021-03081-w

Internet

https://doi.org/10.1186/s12888-021-03081-w

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