Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433

Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433

Cardiac fibrosis is the pathological consequence of fibroblast proliferation and fibroblast-to-myofibroblast transition. As a new class of endogenous non-coding RNAs, circular RNAs (circRNAs) have been identified in many cardiovascular diseases including fibrosis, generally acting as microRNA (miRNA...

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Bibliographic Details
Main Authors: Yujiao Zhu, Wen Pan, Tingting Yang, Xiangmin Meng, Zheyi Jiang, Lichan Tao, Lijun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Genetics
Subjects:
cardiac fibrosis
circNFIB
miR-433
primary adult cardiac fibroblasts
transforming growth factor-β
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00564/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00564/full

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