Phase II Study of Biweekly Pemetrexed Plus Irinotecan as Second-Line Therapy for Metastatic Colorectal Cancer

Background. This open-label, single-arm, two-stage, Phase II study investigated the efficacy and safety of bi-weekly pemetrexed combined with irinotecan, in patients with metastatic colorectal cancer (mCRC), after first-line chemotherapy using FOLFOX regimen. Patients and methods. Patients received...

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Bibliographic Details
Main Authors: C. Louvet, T. André, E. Gamelin, M. Hebbar, M. Mabro, M. Bennamoun, H. Rassam, A. de Gramont
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2010/785934