Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing.

Analyzing cell-free DNA (cfDNA) as a source of circulating tumor DNA is useful for diagnosing or monitoring patients with cancer. However, the concordance between cfDNA within liquid biopsy and genomic DNA (gDNA) within tumor tissue biopsy is still under debate. To evaluate the concordance in a clin...

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Bibliographic Details
Main Authors: Jun-Kyu Kang, Sunghoon Heo, Hwang-Phill Kim, Sang-Hyun Song, Hongseok Yun, Sae-Won Han, Gyeong Hoon Kang, Duhee Bang, Tae-You Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232754