IRF6 Is Directly Regulated by ZEB1 and ELF3, and Predicts a Favorable Prognosis in Gastric Cancer

IRF6 Is Directly Regulated by ZEB1 and ELF3, and Predicts a Favorable Prognosis in Gastric Cancer

Interferon regulatory factor 6 (IRF6) acts as a tumor suppressor and controls cell differentiation in ectodermal and craniofacial tissues by regulating expression of target genes. However, its function in gastric cancer (GC) remains unknown to date. In this study, we found that the IRF6 expression w...

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Bibliographic Details
Main Authors: Dandan Li, Ping Cheng, Jingjie Wang, Xuemei Qiu, Xudong Zhang, Li Xu, Ying Liu, Shanshan Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
IRF6
ELF3
ZEB1
transcriptional regulation
gastric cancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00220/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00220/full

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