The (not so) immortal strand hypothesis

Background: Non-random segregation of DNA strands during stem cell replication has been proposed as a mechanism to minimize accumulated genetic errors in stem cells of rapidly dividing tissues. According to this hypothesis, an “immortal” DNA strand is passed to the stem cell daughter and not the mor...

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Bibliographic Details
Main Authors: Cristian Tomasetti, Ivana Bozic
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115000148