Impact of rituximab on immunoglobulin concentrations and B cell numbers after cyclophosphamide treatment in patients with ANCA-associated vasculitides.

Impact of rituximab on immunoglobulin concentrations and B cell numbers after cyclophosphamide treatment in patients with ANCA-associated vasculitides.

OBJECTIVE: To assess the impact of immunosuppressive therapy with cyclophosphamide (CYC) and rituximab (RTX) on serum immunoglobulin (Ig) concentrations and B lymphocyte counts in patients with ANCA-associated vasculitides (AAVs). METHODS: Retrospective analysis of Ig concentrations and peripheral B...

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Bibliographic Details
Main Authors: Nils Venhoff, Nora M Effelsberg, Ulrich Salzer, Klaus Warnatz, Hans Hartmut Peter, Dirk Lebrecht, Michael Schlesier, Reinhard E Voll, Jens Thiel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3357389?pdf=render

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http://europepmc.org/articles/PMC3357389?pdf=render

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