Role of Downregulation and Phosphorylation of Cofilin in Polarized Growth, MpkA Activation and Stress Response of Aspergillus fumigatus

Role of Downregulation and Phosphorylation of Cofilin in Polarized Growth, MpkA Activation and Stress Response of Aspergillus fumigatus

Aspergillus fumigatus causes most of aspergillosis in clinic and comprehensive function analysis of its key protein would promote anti-aspergillosis. In a previous study, we speculated actin depolymerizing factor cofilin might be essential for A. fumigatus viability and found its overexpression upre...

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Bibliographic Details
Main Authors: Xiaodong Jia, Xi Zhang, Yingsong Hu, Mandong Hu, Xuelin Han, Yansong Sun, Li Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Microbiology
Subjects:
Aspergillus fumigatus
cofilin downregulation
cofilin phosphorylation
polarized growth
cell wall integrity
stress response
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02667/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02667/full

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