Hepcidin-25 in chronic hemodialysis patients is related to residual kidney function and not to treatment with erythropoiesis stimulating agents.

Hepcidin-25 in chronic hemodialysis patients is related to residual kidney function and not to treatment with erythropoiesis stimulating agents.

Hepcidin-25, the bioactive form of hepcidin, is a key regulator of iron homeostasis as it induces internalization and degradation of ferroportin, a cellular iron exporter on enterocytes, macrophages and hepatocytes. Hepcidin levels are increased in chronic hemodialysis (HD) patients, but as of yet,...

Full description

Bibliographic Details
Main Authors: Neelke C van der Weerd, Muriel P C Grooteman, Michiel L Bots, Marinus A van den Dorpel, Claire H den Hoedt, Albert H A Mazairac, Menso J Nubé, E Lars Penne, Carlo A Gaillard, Jack F M Wetzels, Erwin T Wiegerinck, Dorine W Swinkels, Peter J Blankestijn, Piet M Ter Wee, CONTRAST Investigators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3396629?pdf=render

Internet

http://europepmc.org/articles/PMC3396629?pdf=render

Similar Items