Perspective: Identification of genetic variants associated with dopaminergic compensatory mechanisms in early Parkinson's disease

Perspective: Identification of genetic variants associated with dopaminergic compensatory mechanisms in early Parkinson's disease

Parkinson's disease (PD) is slowly progressive, and heterogeneity of its severity among individuals may be due to endogenous mechanisms that counterbalance the striatal dopamine loss. In this perspective paper, we introduce a neuroimaging-genetic approach to identify genetic variants, which may...

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Bibliographic Details
Main Authors: Lior eGreenbaum, Mordechai eLorberboym, Eldad eMelamed, Amihai eRigbi, Yael eBarhum, Yoav eKohn, Alex eKhlebtovsky, Bernard eLerer, Ruth eDjaldetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson's disease
tyrosine hydroxylase
compensatory mechanisms
FP-CIT SPECT
neuroinaging genetics.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00052/full

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http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00052/full

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