Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models.

Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models.

<h4>Background</h4>Signaling through mTOR and somatostatin pathway is implicated in thyroid cancer development.<h4>Method</h4>We evaluated everolimus, an mTOR inhibitor and pasireotide, a multi receptor somatostatin analogue as potential therapy of thyroid cancer focusing on...

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Bibliographic Details
Main Authors: Taofeek K Owonikoko, Guojing Zhang, Shenila B Lallani, Zhengjia Chen, Deborah E Martinson, Fadlo R Khuri, Sagar Lonial, Adam Marcus, Shi-Yong Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0206309

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https://doi.org/10.1371/journal.pone.0206309

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