Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells

Premature senescence, a death escaping pathway for cells experiencing stress, is conducive to aging and cardiovascular diseases. The molecular switch between senescent and apoptotic fate remains, however, poorly recognized. Nrf2 is an important transcription factor orchestrating adaptive response to...

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Bibliographic Details
Main Authors: Aleksandra Kopacz, Damian Klóska, Bartosz Proniewski, Dominik Cysewski, Nicolas Personnic, Aleksandra Piechota-Polańczyk, Patrycja Kaczara, Agnieszka Zakrzewska, Henry Jay Forman, Józef Dulak, Alicja Józkowicz, Anna Grochot-Przęczek
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719303830