IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils

<p>Abstract</p> <p>Background</p> <p>The interplay between IFN-γ, IL-17 and neutrophils during CNS inflammatory disease is complex due to cross-regulatory factors affecting both positive and negative feedback loops. These interactions have hindered the ability to distin...

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Bibliographic Details
Main Authors: Savarin Carine, Stohlman Stephen A, Hinton David R, Ransohoff Richard M, Cua Daniel J, Bergmann Cornelia C
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/104