IL‐12 and IL‐15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells

IL‐12 and IL‐15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells

Abstract Introduction Murine hepatic NK cells exhibit adaptive features, with liver‐specific adhesion molecules CXCR6 and CD49a acting as surface markers. Methods We investigated human liver‐resident CXCR6+ and CD49a+ NK cells using RNA sequencing, flow cytometry, and functional analysis. We further...

Full description

Bibliographic Details
Main Authors: Theresa Hydes, Angela Noll, Gabriela Salinas‐Riester, Mohammed Abuhilal, Thomas Armstrong, Zaed Hamady, John Primrose, Arjun Takhar, Lutz Walter, Salim I. Khakoo
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Immunity, Inflammation and Disease
Subjects:
CD49a antigen
chemokine receptor 6 protein
cytokines
human liver
natural killer cells
Online Access:https://doi.org/10.1002/iid3.190

Internet

https://doi.org/10.1002/iid3.190

Similar Items