Xiaoyaosan Improves Antibiotic-Induced Depressive-Like and Anxiety-Like Behavior in Mice Through Modulating the Gut Microbiota and Regulating the NLRP3 Inflammasome in the Colon

Xiaoyaosan Improves Antibiotic-Induced Depressive-Like and Anxiety-Like Behavior in Mice Through Modulating the Gut Microbiota and Regulating the NLRP3 Inflammasome in the Colon

Disturbance of the gut microbiota plays an essential role in mental disorders such as depression and anxiety. Xiaoyaosan, a traditional Chinese medicine formula, has a wide therapeutic spectrum and is used especially in the management of depression and anxiety. In this study, we used an antibiotic-i...

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Bibliographic Details
Main Authors: Wenzhi Hao, Jiajia Wu, Naijun Yuan, Lian Gong, Junqing Huang, Qingyu Ma, Huizheng Zhu, Hua Gan, Xiaoli Da, Lijuan Deng, Xiaojuan Li, Jiaxu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Xiaoyaosan
antidepressant
anxiolytic
lipopolysaccharide
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.619103/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.619103/full

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