Molecular and Cellular Mechanisms Affected in ALS

Molecular and Cellular Mechanisms Affected in ALS

Amyotrophic lateral sclerosis (ALS) is a terminal late-onset condition characterized by the loss of upper and lower motor neurons. Mutations in more than 30 genes are associated to the disease, but these explain only ~20% of cases. The molecular functions of these genes implicate a wide range of cel...

Full description

Bibliographic Details
Main Authors: Laura Le Gall, Ekene Anakor, Owen Connolly, Udaya Geetha Vijayakumar, William J. Duddy, Stephanie Duguez
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Journal of Personalized Medicine
Subjects:
oxidative stress
mitochondria dysfunction
axonal transport
autophagy
endocytosis
secretion
Online Access:https://www.mdpi.com/2075-4426/10/3/101

Internet

https://www.mdpi.com/2075-4426/10/3/101

Similar Items