Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline

Age-related cognitive decline occurs without frank neurodegeneration and is the most common cause of memory impairment in aging individuals. With increasing longevity, cognitive deficits, especially in hippocampus-dependent memory processes, are increasing in prevalence. Nevertheless, the neurobiolo...

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Bibliographic Details
Main Authors: Heather D. VanGuilder, Julie A. Farley, Han Yan, Colleen A. Van Kirk, Matthew Mitschelen, William E. Sonntag, Willard M. Freeman
Format: Article
Language:English
Published: Elsevier 2011-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000945