HPV DNA in saliva from patients with SCC of the head and neck is specific for p16-positive oropharyngeal tumours

Abstract Background Human papillomavirus (HPV) is an important cause of head and neck squamous cell carcinoma (HNSCC), especially in young people. These tumours overexpress p16 and respond well to treatment. The rapid detection of HPV in patients with HNSCC may expedite treatment when p16 status is...

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Bibliographic Details
Main Authors: Jason K. Wasserman, Ryan Rourke, Bibianna Purgina, Lisa Caulley, Jim Dimitroulakis, Martin Corsten, Stephanie Johnson-Obaseki
Format: Article
Language:English
Published: BMC 2017-01-01
Series:Journal of Otolaryngology - Head and Neck Surgery
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40463-016-0179-6