Self-contained gene-set analysis of expression data: an evaluation of existing and novel methods.

Gene set methods aim to assess the overall evidence of association of a set of genes with a phenotype, such as disease or a quantitative trait. Multiple approaches for gene set analysis of expression data have been proposed. They can be divided into two types: competitive and self-contained. Benefit...

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Bibliographic Details
Main Authors: Brooke L Fridley, Gregory D Jenkins, Joanna M Biernacka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2941449?pdf=render