An antitumor peptide RS17‐targeted CD47, design, synthesis, and antitumor activity

Abstract Background CD47 is a widely expressed transmembrane protein located on the surface of somatic cells. It mediates a variety of cellular processes including apoptosis, proliferation, adhesion, and migration. An important role for CD47 is the transmission of a “Don't eat me” signal by int...

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Bibliographic Details
Main Authors: Xinmin Wang, Ying Wang, Jialiang Hu, Hanmei Xu
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.3768