CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.

CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.

Cytotoxic CD8+ T cells (CTLs) play a critical role in controlling viral infections. HIV-infected individuals develop CTL responses against epitopes derived from viral proteins, but also against cryptic epitopes encoded by viral alternative reading frames (ARF). We studied here the mechanisms of HIV-...

Full description

Bibliographic Details
Main Authors: Sylvain Cardinaud, Gesa Consiglieri, Romain Bouziat, Alejandra Urrutia, Stéphanie Graff-Dubois, Slim Fourati, Isabelle Malet, Julien Guergnon, Amélie Guihot, Christine Katlama, Brigitte Autran, Peter van Endert, François A Lemonnier, Victor Appay, Olivier Schwartz, Peter M Kloetzel, Arnaud Moris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21589903/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21589903/pdf/?tool=EBI

Similar Items