miR-449a Suppresses Tamoxifen Resistance in Human Breast Cancer Cells by Targeting ADAM22

miR-449a Suppresses Tamoxifen Resistance in Human Breast Cancer Cells by Targeting ADAM22

Background/Aims: Most of estrogen receptor positive breast cancer patients respond well initially to endocrine therapies, but often develop resistance during treatment with selective estrogen receptor modulators (SERMs) such as tamoxifen. Altered expression and functions of microRNAs (miRNAs) have b...

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Bibliographic Details
Main Authors: Jun Li, Mingjie Lu, Jiao Jin, Xiyi Lu, Tongpeng Xu, Shidai Jin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tamoxifen resistance
Estrogen receptor
Breast cancer
miR-449a
ADAM22
Online Access:https://www.karger.com/Article/FullText/493964

Internet

https://www.karger.com/Article/FullText/493964

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