Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas

Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas

Medulloblastoma (MB) is the most common malignant pediatric brain tumor, however, the mechanisms underlying tumorigenesis in different MB subgroups remain incompletely understood. Although previous studies of MB predisposition have been conducted in tertiary referral centers primarily in Caucasian c...

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Bibliographic Details
Main Authors: Zaili Luo, Xinran Dong, Jianzhong Yu, Yong Xia, Kalen P. Berry, Rohit Rao, Lingli Xu, Ping Xue, Tong Chen, Yifeng Lin, Jiyang Yu, Guoying Huang, Hao Li, Wenhao Zhou, Q. Richard Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
medulloblastoma
Asian cohort
whole exome sequencing
RNA-seq
subgroup-specific regulator
ZNF124
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.634056/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.634056/full

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