Identification of murine gammaherpesvirus 68 miRNA-mRNA hybrids reveals miRNA target conservation among gammaherpesviruses including host translation and protein modification machinery.

Identification of murine gammaherpesvirus 68 miRNA-mRNA hybrids reveals miRNA target conservation among gammaherpesviruses including host translation and protein modification machinery.

Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), establish lifelong latent infection in B cells and are associated with a variety of tumors. In addition to protein coding genes, these viruses encode numerous microRNAs...

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Bibliographic Details
Main Authors: Whitney L Bullard, Mehmet Kara, Lauren A Gay, Sunantha Sethuraman, Yiping Wang, Shreya Nirmalan, Alim Esemenli, April Feswick, Brett A Hoffman, Rolf Renne, Scott A Tibbetts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007843

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https://doi.org/10.1371/journal.ppat.1007843

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